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a recent New York Times poll of over 2,000 GLP-1 users found that most were enthusiastic about their experience on the medications, with 63 percent saying the drugs had relieved the conditions they were treating

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Thats why lean-mass preservation studies are becoming more common, especially in high-risk and older populations. He then reviewed three key trials ( Figure 3 ): Scholar Rocks EMBRAZ study : a 24-week trial adding the myostatin inhibitor apitegromab to tirzepatide, which successfully preserved 15% more lean mass compared to tirzepatide alone Verus QUALITY study : using enobosarm, a selective androgen receptor modulator, combined with semaglutide, preserved about 20% more lean mass and significantly improved physical function Rivus HuMAIN study : tested HU6 in patients with obesity-related heart failure with preserved ejection fraction (HFpEF), showing reduced fat mass without significant loss of lean mass In addition, Eli Lillys BELIEVE Phase II trial combined semaglutide with bimagrumab, a dual ActRII antibody blocking activin and myostatin pathways