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Description

KARs are composed of GluK1-GluK5 subunits, with subunits GluK1-GluK3 forming functional homo- and heteromeric channels, while GluK4-GluK5 assemble as obligate heteromers, partnering with subunits GluK1-GluK3

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After binding to its cell membrane receptor, TNF activates NF-B in the following sequence: (a) phosphorylation of the inhibitor of NF-B (IB-) by IKK

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