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Increased Nausea: Both GLP-1 agonists and alcohol can irritate the stomach lining, leading to nausea

In clinical trials, patients achieved weight loss of approximately 15-20% from baseline after 72 weeks, with results varying by dose and whether patients had diabetes

Try the BMI Calculator Dual-receptor weight loss: GIP and GLP-1 activation together produce 20%+ weight loss that doesn't depend on thyroid metabolic rate Visceral fat reduction: Targets the inflammatory abdominal fat that's disproportionately improved in hypothyroid patients Inflammation suppression: 30% to 40% reduction in CRP may ease systemic autoimmune symptoms Insulin resistance correction: Restores glucose metabolism toward normal ranges, achieving weight loss that was previously blocked Cardiovascular risk reduction: Improves lipid profiles, blood pressure, and metabolic markers that are commonly improved in Hashimoto's Important Safety Information Thyroid C-Cell Warning Like all GLP-1 receptor agonists, Zepbound carries a boxed warning about thyroid C-cell tumors (medullary thyroid carcinoma, or MTC) found in animal studies