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Unlike other digital programs that rely exclusively on behavior change, Digbi GLP-Fit is based on recognition by the National Institutes of Health (NIH) and medical research institutions like Harvard Health that genetics account for up to 80% of the risk of obesity and that an individual's insulin resistance and gut-microbiome are essential factors in addressing obesity

In the series by Wong et al , 45 regional metastases developed in one patient, local recurrence in three, and three were reported to be alive and well with no evidence of disease after excision

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