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The impact of GLP-1 analogs on muscle mass is of particular concern, as a reduction in muscle mass can lead to sarcopenia, which negatively affects metabolic health and increases the risk of frailty in the elderly

Hussaini S, Chehade R, and Boldt RG, et al (2021) Association between immune-related side effects and efficacy and benefit of immune checkpoint inhibitors a systematic review and meta-analysis Cancer Treat Rev 92 102134 53