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2.1 Sperm DNA damage and abnormal sperm morphology Chronic hyperglycemia and insulin resistance lead to systemic immune dysregulation and sustained inflammation within the male reproductive tract ( 2.2 Reduction in sperm count DM, particularly T2DM, significantly reduces sperm count through multiple interrelated mechanisms
116,117,118 Notably, several studies have shown that MeCP2 binds with chromatin and transcriptional activators at the promoter of an activated target to activate gene expression, which means that MeCP2 can operate as both an activator and a repressor of transcription
J Am Coll Cardiol, 2010
Unlike a muscle strain that typically heals within weeks, fascial injuries can persist for months or even years
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