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Experimental Plasma Samples For plasma, 100 L of sample was added to a microcentrifuge tube along with 5 L of internal standard (5 ng/mL of internal standard working stock containing the D3 internal standards shown in Table I)

[10] [11] Clinical trials have demonstrated that tirzepatide produces substantial reductions in hemoglobin A1C (often exceeding 2 percentage points) in patients with type 2 diabetes

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