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Goodman NF, Cobin RH, Futterweit W, Glueck JS, Legro RS, Carmina E, American association of clinical endocrinologists, american college of endocrinology, and androgen excess and pcos society disease state clinical review: guide to the best practices in the evaluation and treatment of polycystic ovary syndrome

it also found increasing memory impairment as B12 levels dropped even whilst within currently defined acceptable ranges and that B12 interventions are effective once levels are less than 300 pmol/L

Individuals with aldehyde dehydrogenase 2 (ALDH2) deficiency, most prevalent in East Asian populations, accumulate acetaldehyde during alcohol metabolism, producing severe flushing, tachycardia, and nausea even at low intake levels

Moderate alcohol consumption is defined as no more than 2 drinks/day for men and no more than 1 drink/day for women