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While taste changes during treatment with GLP-1 receptor agonists or dual GIP/GLP-1 receptor agonists are generally benign and self-limiting, certain situations warrant medical evaluation to rule out complications or alternative diagnoses

Additionally, Ex-4 has been demonstrated to reduce extracellular signal-regulated kinase (ERK)-mitogen-activated protein kinases (MAPK) phosphorylation in LNCaP prostate cancer cells [17]

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Recognizing this distinction can shift the approach from frustration to strategy and from not working to working well