In selective autophagy, palmitoylation can function as a recruitment signal or a protective shield. On the one hand, DHHC19-mediated palmitoylation of the selective autophagy receptor p62 at Cys289 and Cys290 enhances the affinity of p62 droplets for the autophagosomal membrane, which promotes cargo degradation [139]
It acts by binding to nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction, causing prolonged depolarization of skeletal muscle cells
In rates, they negatively affect the liver, lungs, and kidneys, while in horses, their exposure can lead to equine leukoencephalomalacia (ELEM), a fatal neurological disease characterized by various symptoms [76]
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