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NRF2 is tightly regulated at different levels by epigenetic modifications such as OS, inflammation, and different forms of stress [148], and has regulatory functions in mitochondrial biogenesis and cellular energy metabolism [149]

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Common Concentrations Used in Published Research Published in-vitro work commonly uses GHK-Cu at concentrations between 10 nM and 10 M in fibroblast culture, with 1 M representing a frequently reported working concentration [2][3]