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Alongside elecoglipron, we continue to advance our broader portfolio of different mechanisms, including a selective Amylin receptor agonist, AZD6234, as a monotherapy and in combination with our dual GLP-1/glucagon receptor agonist, AZD9550, both of which are expected to deliver first Phase II data this year

Interestingly, rats deprived of vitamin D exhibited even greater deficits in synaptic strength, as measured by reduced field excitatory postsynaptic potential amplitudes in the hippocampal CA3CA1 circuit