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Adequate time should be allowed without straining, and the urge to defecate should never be ignored or delayed when possible

However, approval criteria do not mean all patients at these thresholds require the medicationclinical judgment, patient preference, and metabolic history guide the decision to initiate therapy

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The individual components methionine, inositol, and choline are recognized nutrients, but the specific injectable combination has received no FDA endorsement as a weight loss treatment