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Obesity is on the rise globally, with roughly 20% of ICU patients suffering from it [1]

Insulin sensitivity improves and androgen levels fall Chronic metabolic strain can cause insulin resistance, a hallmark of PMOS

Supplementation with aged garlic extract improves both NK and -T cell function and reduces the severity of cold and flu symptoms: a randomized, double-blind, placebo-controlled nutrition intervention

Hyperinsulinemia and ectopic lipid accumulation promote activation of pro-inflammatory pathways, including Nuclear Factor kappa-light-chain-enhancer of activated B cells (NF-B) signaling and NLRP3 inflammasome activation, which in turn exacerbate loss of immune tolerance [52,53]