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Conversely, Nrf2 has been documented to reduce NOX activation and inhibit protein kinase C, consequently leading to a decrease in ROS levels and production in Nrf2-KO mice due to elevated antioxidant GSH levels, highlighting its role in mitigating oxidative stress

Dehydration also reduces the production of synovial fluid, which lubricates your joints and connective tissues, further contributing to the risk of fascial restrictions and conditions like plantar fasciitis

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