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Safety Considerations, Side Effect Management, and Who This Treatment Applies To Semaglutide is indicated for chronic weight management in adults with obesity (BMI 30) or overweight (BMI 27) with weight-related comorbidities

Recognise the importance of maintaining glutathione levels as part of their dietary intake

Patients should be educated about hypoglycemia recognition and management, including the importance of monitoring for signs of and managing hypoglycemia

The study, published in Scientific Reports (Liu et al., 2025), systematically extracted and analyzed adverse drug reactions associated with concomitant administration of GLP-1 RAs and metformin for the first time using FAERS data spanning two decades (20042024), encompassing 48,214 adverse drug reaction reports