Annals of the New York Academy of Sciences, 1100, 383386
The PRCC analysis also shows that the process of ROS detoxification by GSH has strong effect on the level of [ROS] during the development of both healthy and diseased retinas
Vitamin B12 Why it matters: Found naturally in animal foods, vitamin B12 regulates key metabolic processes in the body both directly and as a cofactor (or "helper molecule") for two enzymes (methionine synthase and L-methylmalonyl-coenzyme A mutase)
In turn, this may contribute to the development of depression by increasing oxidative stress, DNA damage, and cell death in the body ( A 2020 study with 132 children and teens, 89 with and 43 without depression, found that the participants with depression had lower B12 levels and higher levels of homocysteine compared with those without depression ( In addition to depressive symptoms, low or deficient B12 levels may lead to other mental conditions, including psychosis and mood disorders ( Because a deficiency in B12 negatively impacts the central nervous system, people with low or deficient B12 levels may feel foggy-headed and have difficulty concentrating and completing tasks ( Fortunately, studies show that mental impairment related to low B12 levels can improve with B12 treatment
