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In February 2026, HHS Secretary Kennedy announced the expected reclassification of approximately 14 Category 2 peptides including GHK-Cu to Category 1, which would enable prescription compounding, though formal FDA rulemaking had not yet been completed at that time [1]

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However, the limited follow-up duration of 6 months raised concerns about potential reverse causality, as undetected suicidal ideation and medical conditions might have influenced the choice of particular anti-obesity or anti-diabetic drugs

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