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However, GLP-/GIP dual agonists have been proved to be orally effective in animal experiments, and its state in plasma is more stable than GLP-1RA [141], and this oral administration method has gradually been applied to the clinic [142]

This came shortly after Lillys obesity treatment Zepbound outperformed rival Novo Nordisks Ozempic and Wegovy in a head-to-head weight loss study published in JAMA Internal Medicine .

Patients who maintain results after GLP-1 treatment are typically those who used the medication window to build muscle, stabilize blood sugar, and address the metabolic patterns underneath