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In my recent piece on supplements for hypothyroidism, I referenced an experimental study demonstrating that L-Carnitine ( one form of supplemental carnitine) may reduce fatigue in those living with hypothyroidism

88 Uridine diphosphate-glucuronosyltransferases are responsible for converting many exogenous, endogenous lipophilic compounds and xenobiotics into more polar substances so that they can be readily excreted from the body through bile and urine