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Discontinuation of treatment or switching between agents should be reserved for patients with persistent or severe symptoms despite optimised management strategies

The infection spread rapidly, first in drug users and then in the general population, and did not stabilize until the 1980s.47 Since the exclusion of paid blood donors was not mandatory until the late 1980s,49 HCV identification was not possible until 198950 and first-generation ELISA was not applied in blood banks until 1991.51 As a result, there was time enough for genotype 4 infection to spread into the general population by mechanisms other than IDU

The patients who perform best during GLP-1 therapy are usually not the ones relying on the medication alone

Current restrictions in Europe and the USA The rules in the United States changed drastically in 2022