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The data shows that Tadalafil has an IC50 of 1.6 nM for PDE5, which is much lower than the inhibitory concentration for other subtypes such as PDE1 (IC50=2100 nM) and PDE6 (IC50=180 nM), providing a molecular basis for its specificity in the treatment of erectile dysfunction (ED)

By regulating the microbial composition and immune response, supplying energy to intestinal epithelial cells, and alleviating intestinal fibrosis, F

Data analysed by two-way repeated measures ANOVA to assess main effects of treatment ( b and c )

Checking your stools texture is important: If you have diarrhoea, your stool will be soft and loose