starter dose tirzepatide (Zepbound, Mounjaro): Weight Loss, Diabetes, Dosage & Side Effects What Is Zepbound (tirzepatide)? Uses,

in vivo and/or ex vivo / HematologySickle cell diseasePhase I-EnablingBeta-thalassemiaPhase I-Enabling In vivo HSC editingHbF activation / In vivo LNP base editing / HematologySickle cell diseaseResearchBeta-thalassemiaResearch BEAM-302BEAM-302 / SERPINA1 E342K/PiZ mutation correction / In vivo LNP base editing / Liver-targeted genetic diseasesAlpha-1 antitrypsin deficiencyPhase I/IIOngoing Phase 1/2 trial

One more note: if you're pregnant, high doses of Vitamin A can be a concern, so a lot of people skip topical retinoids (including Retinyl Palmitate) during pregnancy just to be safe

The replacement of glycine with alanine at the 15th position is thought to possibly increase bioactivity

Hirsch A, Hahn D, Kempn P, Hofer G, Nuoffer JM, Mullis PE, Flck CE