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some experts say to NEVER take any direct-acting antioxidants (vitamin A, C, E, NAC, etc.) with SFN (or within a 24-hour window ) as these direct-acting antioxidants will prevent the release of NRF2 as it's the actual pro-oxidant effect of SNF that causes the release of NRF2 and that will be neutralized by these direct-acting antioxidants

Glutathione is a naturally occurring antioxidant produced by the body, with particularly high concentrations in the liver, where it plays a vital role in detoxification and protecting cells from damage

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