can semaglutide cause blood clots GLP-1 RA's Increase Clot Risks Wegovy® Lawsuit | July 2026

Safety data is similarly limited, with the tolerability of creams and long-term effects sparsely analyzed in the literature

A follow-up post hoc analysis identified improvements in fibrosis-related biomarkers in the dulaglutide group, including lower serum PRO-C6 levels for type VI collagen formation and higher urine C3M levels for type III collagen degradation (74)

Adverse effects with supratherapeutic doses and therapeutic errors appear to be largely an extension of those seen with therapeutic use, and the majority of unintentional exposures to GLP-1 RAs can likely be safely monitored at home

In research it is studied for melanocyte signaling, pigmentation pathway research, and photoprotection model systems