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73 Patients with major depression and anxiety disorders had lower plasma uric acid levels and increased UA levels after treatment, further suggesting that UA may have a neuroprotective effect

Pharmacokinetics of IGF-1 LR3 The extended half-life of IGF-1 LR3 stems from two features: the N-terminal extension physically blocks IGFBP binding, and reduced clearance via the IGFBP-ALS ternary complex slows hepatic filtration

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