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Sources: [1] Vanyushin, et al

doi: 10.1038/nri1350

If gastrointestinal symptoms are troublesome, discuss with your prescriber whether: Slowing the rate of dose escalation might be appropriate Anti-emetic medication could help manage nausea Dietary advice from a dietitian might optimise symptom control For constipation, ensure adequate fluid intake, increase dietary fibre gradually, and maintain physical activity