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The amount of food intake was monitored at HFD period (16 weeks) to assess consumption and changes in body weight from baseline to post-intervention (HFD) was calculated

SURMOUNT-1 results (72 weeks, adults with obesity): 5 mg dose: approximately 15% body weight loss 10 mg dose: 19.5% body weight loss 15 mg dose: 22.5% body weight loss Placebo: 3.1% body weight loss At the 15 mg maximum dose, the average participant lost about 52 pounds over 72 weeks

To compensate for the bodys decreased red blood cell count, the heart may begin to beat more quickly

But some studies mention the cases of recurrent miscarriages due to increased IL-12 levels