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Schlezinger JJ, Struntz WD, Goldstone JV, Stegeman JJ: Uncoupling of cytochrome P450 1A and stimulation of reactive oxygen species production by co-planar polychlorinated biphenyl congeners

The LIRA-RENAL Trial (Once-Daily Liraglutide) The Efficacy and Safety of Liraglutide Versus Placebo as Add-on to Glucose-Lowering Therapy in Patients With Type 2 Diabetes and Moderate Renal Impairment (LIRA-RENAL) trial investigated the efficacy and safety of liraglutide as an add-on to existing glucose-lowering medications in people with inadequately controlled T2DM and moderate renal impairment (stage 3 CKD, eGFR 3059 ml/min/1.73 m 2 ) [48]

Frame the submission around disease prevention: highlight how GLP-1 therapy reduces heart attack and stroke risk by 20% in clinical trials, not just weight loss

Semaglutide shots combined with Houstons infrastructure create optimal conditions for sustainable progress year-round