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This article compares what is actually documented in the peer-reviewed record for each, states each compounds regulatory reality plainly, and is explicit about the single most important honesty point: no published head-to-head trial has ever compared cagrilintide directly against retatrutide

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Cagrilintide acts on amylin receptors in the hindbrain to suppress appetite, slow gastric emptying, and reduce postprandial glucagon secretion

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