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Our 2025 study in JMIR Formative Research examined 12-month outcomes for participants using semaglutide with our behavioural support programme and found 1 : 19.1% average weight loss at 12 months for participants who maintained an active subscription 77.7% achieved at least 10% weight loss 61.5% achieved at least 15% weight loss 69% reported no side effects by month 12 Separately, an NHS-published evaluation in the BMJ found that Second Nature achieved substantially higher weight loss than four other providers in the National Diabetes Prevention Programme

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