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All four of these inhibitors reduce the reabsorption of filtered glucose, decrease the renal threshold for glucose, and promote urinary glucose excretion. Studies show that SGLT-2 use in diabetic kidney transplant recipients resulted in a decrease in hemoglobin A1C. There were potential side effects including increased infection risk and fluctuating allograft function

That's why keeping Ozempic below 86F is so important higher temperatures can degrade it, making it less effective at controlling your blood sugar or helping with weight loss

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