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Description

Its levels decline with age

95% CI: 2.52 to 1.42) also failed to show meaningful differences compared to placebo

Beta cell mitochondria play a key role in this process, not only by providing energy in the form of ATP to support insulin secretion, but also by synthesising metabolites (anaplerosis) that can act, both intra- and extramitochondrially, as factors that couple glucose sensing to insulin granule exocytosis