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Immunometabolism is an emerging research field in which immune cells regulate energy and biosynthesis through pathways such as glycolysis, oxidative phosphorylation, and tricarboxylic acid cycle in different microenvironments to meet proliferation, differentiation, and effector functions (18)

Grant, C.M., F.H

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Studies in genetically engineered animals may thus underestimate the number of GLP-1R populations in the brain involved in feeding, because, for illustration, it is intrinsically difficult to show whether a sub-population of brain GLP-1Rs mediates 10 or 20% of an effect