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The combination of a glucagon-like peptide-1 receptor (GLP-1) agonist plus basal insulin offered the ideal triumvirate, according to Laura Young and John Buse from the University of North Carolina, USA, in an accompanying commentary to the meta-analysis [2]

Inclusion of case-control studies, which are more susceptible to bias, may explain these discrepancies among meta-analyses (128)

The peptides discussed by the advisory committee were formerly identified by the FDA as posing significant safety risks, and the vote to loosen restrictions has stirred controversy in medical circles

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