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Acknowledgements This work is supported by National Nature Foundation of China (81371988), Zhejiang Provincial Health Department Foundation of China (2016KYB196 and LY15H060008)

One study from Liu-Ambrose et al observed significant reductions in global brain volume following 1 year of high-intensity progressive RT (2 sets of 6-8 repetitions at 70%85% of 1RM, either once or twice weekly) in older women free from MCI (Liu-Ambrose et al., 2010)