CVD: Cardiovascular Disease Although several in-line GLP-1 and glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 RAs have approved indications beyond T2D and overweight/ obesity, US Pharmacopeia Drug Classification (USP DC) 2025 limits classification to categories/classes according to their primary diagnosis (e.g., antidiabetic
A study examining weight outcomes in patients using GLP-1 agonists found that those concurrently taking any antidepressant, including bupropion, lost slightly less weight on average compared to those not taking antidepressants
You'll also want to watch for symptoms that might suggest liver issues, such as: Fatigue Jaundice (yellowing of the skin and eyes) Dark urine Itchy skin Stomach pain and swelling Swelling in the legs and ankles Pale stool color Chronic nausea Alert your healthcare provider to any of these symptoms as soon as you notice them
Insurance companies like Aetna, Cigna, United Healthcare, BlueCross BlueShield, Molina, and Oscar Insurance cover Wegovy, but most of them require prior authorization (PA) before they pay for it
