For the past few years, it has been shown that TMAO, a metabolizing substance of the intestinal flora, has a potential effect in the development of atherosclerosis (Koeth et al., 2014), Dietary phospholipases such as phosphatidylcholine or carnitine are metabolized by the enzyme complex of the intestinal microbiota to produce TMA (Zeisel and Warrier, 2017), and then TMA is further metabolized by the hepatic enzymes of the host through the portal circulation, and converted in the liver to TMAO (Figure 3
Heinrich Caro synthesized Methylene Blue in 1876, originally used as a dye for cotton, wool, and paper
References: Powers AC, DAlessio D
Designed for quick use, the L- Carnitine supplement liquid is easy to measure, consume, and integrate into your daily routine