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This review aims to fill these gaps by offering a comprehensive assessment of GSHs dual role in cancer biology, systematically examining nanotechnology-enabled approaches (such as disulfide and diselenide linkages, transition metal systems, and prodrugs), and critically evaluating their strengths, limitations, and potential for clinical translation

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Melanotan-1 is a linear 13-amino acid chain (molecular weight 1646.85 Da), while Melanotan-2 is a cyclic 7-amino acid peptide (1024.18 Da) with a lactam bridge between positions 4 and 10