Besides exposure to environmental chemicals, perinatal factors such as low birth weight [29], the gut microbiome [30,31,32,33,34,35], and maternal diet [36,37,38] are also attributed to the progression of autoimmune diseases
Stress can exacerbate existing psoriasis or even trigger its onset ( Obesity: Adipose tissue in obese individuals can promote the production of pro-inflammatory cytokines, potentially contributing to the chronic inflammation characteristic of psoriasis ( Infections: Some researchers suggest a possible role for infections, particularly those involving streptococcal bacteria, in triggering guttate psoriasis ( Other environmental factors: While the evidence is less conclusive, alcohol consumption and certain medications have also been implicated in psoriasis pathogenesis ( 3.2 Current psoriasis treatment landscape: progress and challenges Psoriasis treatment strategies are tailored to disease severity, patient characteristics, and treatment efficacy and safety profiles ( 3.2.1 Conventional systemic treatments Psoriasis is traditionally treated with methotrexate, a systemic medicine known for its cytotoxic, anti-inflammatory, and immune-modulatory effects, making it therapeutically valuable
The app also offers weight loss plans and community support features
The teens who reported using cannabis in the past year were about twice as likely to be diagnosed later with a psychotic or bipolar disorder
