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The CANVAS trial found canagliflozin to increase the risk of fractures and lower limb amputation, which was not confirmed in further trials

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Consistently, pharmacological inhibition by A 2A R antagonists has been found to improve motor behavior deficits in PD and dyskinesia [20]

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Second messenger signaling: quantifying pathway outputs such as cAMP accumulation and kinase activation (e.g., ERK) under controlled conditions

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Yang J, Ren J, Song J, Liu F, Wu C, Wang X, et al

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