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People with gastroparesis may experience: Abdominal pain Belching Feeling full immediately when eating Heartburn Nausea Poor appetite Vomiting These symptoms may lead to additional complications, including: Dehydration Difficulty controlling blood sugar levels Malnutrition Novo Nordisk has acknowledged that Wegovy can cause delayed gastric emptying

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Even though tirzepatide is a potent activator of GIP receptor, the contribution of GIP receptor to its overall metabolic effects is not fully understood, although effects on adipose tissue are probably important (Samms et al., 2020)