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There is no licensed formulation, no marketing authorisation, and no completed phase 3 dataset in the public domain

While some patients report fewer side effects with compounded semaglutide, the limited long-term data and absence of standardized quality controls warrant careful consideration when choosing between these options

For GLP-1 RAs, proposed mechanisms of action include an anti-atherothrombotic effect, as well as amelioration of inflammatory markers, resulting in the enhanced retardation of atherosclerosis [60, 124]

Unlicensed peptides purchased online may be counterfeit, contaminated, or incorrectly dosed