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GLP-1, an anorexigenic hormone, is secreted by enteroendocrine cells in the gastrointestinal tract and by preproglucagon neurons in the brain, which together constitute the peripheral and central components of the GLP-1 system

A 2010 paper in Annals of the New York Academy of Sciences by Goldstein et al

Celebrities, social media and press coverage drove demand for a medication that was, technically speaking, a diabetes drug being used off-label for weight management

The guidelines further state that 5-ARIs are appropriate and effective alternatives for men with LUTS secondary to BPH who have demonstrable prostate enlargement