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Pinto RE, Bartley W

Retrograde Mitochondrial-Nuclear Signaling One interesting feature of MOTS-c biology is that MOTS-c seems to travel to the nucleus of cells under conditions of stress and alter the expression of nuclear genes that control antioxidant defences as well as metabolic programs

Here, our study elucidated the pivotal role of GGCT in driving hepatocellular cancer (HCC) and prostate cancer (PCa) progression by orchestrating Gln partitioning between redox homeostasis and the TCA cycle

It does this primarily by suppressing vasopressin production, which in turn makes your kidneys behave as though your body has too much water - resulting in the production of far more urine than normal