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[67] Cardiovascular disease [edit] Increased IGF1 levels are associated with a 16% lower risk of cardiovascular disease and a 28% reduction of cardiovascular events

Another, smaller scale study found similar results in bovine ticks that had been selected for ivermectin resistance (through exposure to sublethal doses of ivermectin) after analysing the ABC transporter transcriptome, where they also found that these genes were significantly upregulated (Pohl et al

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Brain & Nerve Health Research suggests IGF-1 plays a role in cognitive function and neuroprotection, potentially reducing neurodegenerative risks