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10.7717/peerj.6153 16 Heilmann-HeimbachS.HeroldC.HochfeldL

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Synthetic analogue of insulin-like growth factor 1 (IGF-1) studied in cellular growth and signalling research Engineered with an extended amino acid sequence and reduced binding affinity to IGF binding proteins compared to native IGF-1 Investigated in laboratory models involving cell proliferation, differentiation, and metabolic signalling pathways Supplied as high purity lyophilised peptide powder Form: Lyophilised peptide powder Strength: 1mg Purity: 99% Verification: HPLC and Mass Spectrometry

This resulted in a decrease in beta-adrenergic receptor-stimulated PKA activation and decreased activating phosphorylation of perilipin A and HSL (56)