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Lovelle emphasizes that lifestyle interventions are critical to long-term success

The selenoprotein family of iodothyronine deiodinases consists of three enzymes, D1, D2 and D3, which are specifically distributed in tissues and regulate the activation and inactivation of TH: type 1 and 2 deiodinases (D1/D2) catalyse the conversion of the inactive precursor thyroxine (T4) to the active form, triiodothyronine (T3), while type 3 deiodinases (D3) terminate the hormones action by degradation ( 5 Hcy and thyroid diseases 5.1 Hcy and thyroid nodules In recent decades, with the widespread availability of ultrasound technology, thyroid nodules have become a common clinical disease

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This variability restricted the possibility of conducting a meta-analysis and emphasized the need for standardized protocols in future research