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The authors suggest that the improvement in skin water content following the ingestion of collagen peptides was attributed to an increase in the level of NMF constituents in the SC [38]

6.4 Summary of RCTs In the RIPENACTB trial, adjunct NAC treatment with 1,200 mg twice a day in hospitalized HIV/TB patients significantly reduced circulating lipid peroxidation (malondialdehyde (MDA) levels by approximately 40%50%) and increased antioxidant defenses, including glutathione (GSH, by approximately 30%40%), compared to baseline and the standard care group

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