PLoS Pathog (2011) 7:e1001271.10.1371/journal.ppat.1001271 Summary Keywords inflammation, innate immunity, TLR4, macrophages, glutathione, redox regulation, antiviral immunity, influenza Citation Diotallevi M, Checconi P, Palamara AT, Celestino I, Coppo L, Holmgren A, Abbas K, Peyrot F, Mengozzi M and Ghezzi P (2017) Glutathione Fine-Tunes the Innate Immune Response toward Antiviral Pathways in a Macrophage Cell Line Independently of Its Antioxidant Properties
This sudden release can lead to suboptimal drug concentrations at the intended target site in the body, diminishing the drugs therapeutic effect [339]
Ethics declarations Competing Interests The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper
J Biol Chem 2004;279:55008-16